1,3,4,5-Tetrahydro-7-chloro-5-phenyl-2H-1,4-benzodiazepin-2-one
Names
[ CAS No. ]:
1824-69-7
[ Name ]:
1,3,4,5-Tetrahydro-7-chloro-5-phenyl-2H-1,4-benzodiazepin-2-one
[Synonym ]:
7-Chlor-2-oxo-5-phenyl-1.2.3.4-tetrahydro-5H-1.4-benzodiazepin
5-phenyl-7-chloro-1,3,4,5-tetrahydro-2H-1,4-benzodiazepine-2-one
7-chloro-5-phenyl-1,3,4,5-tetrahydro-2H-1,4-benzodiazepin-2-one
2H-1,4-BENZODIAZEPIN-2-ONE,7-CHLORO-5-PHENYL-1,3,4,5-TETRAHYDRO
7-Chlor-1,3,4,5-tetrahydro-5-phenyl-2H-1,4-benzodiazepin-2-on
7-Chlor-1,2,4,5-tetrahydro-5-phenyl-3H-1,4-benzodiazepin-2-on
Ro 5-2181
7-chloro-5-phenyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-2-one
7-Chloro-1,3,4,5-tetrahydro-5-phenyl-2H-1,4-benzodiazepin-2-one
2H-1,4-Benzodiazepin-2-one,1,3,4,5-tetrahydro-7-chloro-5-phenyl
1,3,4,5-Tetrahydro-7-chloro-5-phenyl-2H-1,4-benzodiazepin-2-one
Chemical & Physical Properties
[ Density]:
1.247g/cm3
[ Boiling Point ]:
440.8ºC at 760 mmHg
[ Molecular Formula ]:
C15H13ClN2O
[ Molecular Weight ]:
272.73000
[ Flash Point ]:
220.4ºC
[ Exact Mass ]:
272.07200
[ PSA ]:
41.13000
[ LogP ]:
3.43790
[ Vapour Pressure ]:
5.73E-08mmHg at 25°C
[ Index of Refraction ]:
1.597
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DF2275000
- CHEMICAL NAME :
- 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-phenyl-1,3,4,5-tetrahydro-
- CAS REGISTRY NUMBER :
- 1824-69-7
- BEILSTEIN REFERENCE NO. :
- 0753609
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C15-H13-Cl-N2-O
- MOLECULAR WEIGHT :
- 272.75
- WISWESSER LINE NOTATION :
- T67 GMV JM&TJ CG KR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 154,131,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 335 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,168,1972
Safety Information
[ HS Code ]:
2933990090
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%