MitoPQ

Names

[ Name ]:
MitoPQ

[Synonym ]:
1-Methyl-1'-[10-(triphenylphosphonio)decyl]-4,4'-bipyridinium triiodide
MitoPQ
4,4'-Bipyridinium, 1-methyl-1'-[10-(triphenylphosphonio)decyl]-, iodide (1:3)

Biological Activity

[Description]:

MitoPQ is a mitochondria-targeted redox cycler. MitoPQ produces superoxide by redox cycling at the flavin site of complex I, selectively increasing superoxide production within mitochondria. MitoPQ can be used in antioxidant study[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS

[References]

[1]. Robb EL, et al. Selective superoxide generation within mitochondria by the targeted redox cycler MitoParaquat. Free Radic Biol Med. 2015 Dec;89:883-94.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₉H₄₆I₃N₂P

[ Molecular Weight ]:
954.48

[ Exact Mass ]:
954.053223