MMV674850

Names

[ CAS No. ]:
1820874-51-8

[ Name ]:
MMV674850

Biological Activity

[Description]:

MMV674850 is potent against asexual stage parasites at 2.7 and 4.5 nM and preferentially targets early-stage gametocytes (early-stage gametocyte: IC50 4.5 ± 3.6 nM; late-stage gametocyte: IC50 28.7 ± 0.2 nM).

[References]

[1]. Niemand J, et al. Chemogenomic Fingerprints Associated with Stage-Specific Gametocytocidal Compound Action against Human Malaria Parasites. ACS Infect Dis. 2021 Oct 8;7(10):2904-2916.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₀N₂O₄S₂

[ Molecular Weight ]:
452.55

Related Compounds

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