7-Methoxy obtusifolin

Names

[ CAS No. ]:
1820806-09-4

[ Name ]:
7-Methoxy obtusifolin

Biological Activity

[Description]:

7-Methoxy obtusifolin (Compound 4) is a competitive tyrosinase inhibitor with an IC50 of 7.0 μM[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> Tyrosinase

[Target]

IC50: 7.0 μM (Tyrosinase)[1]

[In Vitro]

7-Methoxy obtusifolin (Compound 4; 10 μM; 48 h) 阻断 α-MSH 诱导的 B16F10 细胞黑色素生成[1]。 7-Methoxy obtusifolin (10 μM; 48 h) 通过抑制 TRP-2 表达抑制黑色素生成[1]。

[References]

[1]. Lee GY, et al. Tyrosinase inhibitory components from the seeds of Cassia tora. Arch Pharm Res. 2018 May;41(5):490-496.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₄O₆

[ Molecular Weight ]:
314.29

Related Compounds

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