2-Bromo-4,6-dinitroaniline
Names
[ CAS No. ]:
1817-73-8
[ Name ]:
2-Bromo-4,6-dinitroaniline
[Synonym ]:
2-bromo-4,6-dinitrobenzenamine
Aniline,2-bromo-4,6-dinitro
EINECS 217-329-2
2,4-Dinitro-6-bromanilin
2,4-dinitro-6-bromo-aniline
2-Bromo-4,6-dinitroaniline
2-bromo-4,6-dinitro-aniline
Bromo DNA
Benzenamine,2-bromo-4,6-dinitro
2-Bromo-4,6-dinitroaminobenzene
6-Bromo-2,4-dinitroaniline
Benzenamine, 2-bromo-4,6-dinitro-
MFCD00007146
Chemical & Physical Properties
[ Density]:
2.0±0.1 g/cm3
[ Boiling Point ]:
400.8±40.0 °C at 760 mmHg
[ Melting Point ]:
148-153 ºC
[ Molecular Formula ]:
C6H4BrN3O4
[ Molecular Weight ]:
262.018
[ Flash Point ]:
196.2±27.3 °C
[ Exact Mass ]:
260.938507
[ PSA ]:
117.66000
[ LogP ]:
3.09
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.707
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BW9303000
- CHEMICAL NAME :
- Aniline, 2-bromo-4,6-dinitro-
- CAS REGISTRY NUMBER :
- 1817-73-8
- BEILSTEIN REFERENCE NO. :
- 0916722
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C6-H4-Br-N3-O4
- MOLECULAR WEIGHT :
- 262.04
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4100 mg/kg
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS Behavioral - somnolence (general depressed activity) Nutritional and Gross Metabolic - weight loss or decreased weight gain
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 10 ug/plate
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 9(Suppl 9),1,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7087 No. of Facilities: 25 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 737 (estimated)
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
F:Flammable;
[ Risk Phrases ]:
R11
[ Safety Phrases ]:
S37/39-S26-S16
[ RIDADR ]:
1325.0
[ WGK Germany ]:
2
[ RTECS ]:
BW9303000
[ Hazard Class ]:
4.1
[ HS Code ]:
2921420090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921420090
[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Anal. Bioanal. Chem 391(5) , 1821-35, (2008)
The development and characterization of one rat monoclonal antibody (mAb) for 2,4-dinitroaniline and of two rat mAbs for 2,6-dinitroaniline are described. With the immunization of rats with 2,4,6-trin...
Inter-laboratory evaluation of the bioluminescent Salmonella reverse mutation assay using 10 model chemicals.Mutagenesis 24(5) , 433-8, (2009)
We have developed the bioluminescent Salmonella reverse mutation assay as a tool for detecting mutagenicity applicable for high-throughput screening of new chemicals. In this study, we report the inte...
Disposition and metabolism of 2-bromo-4,6-dinitroaniline in the male F344 rat.J. Toxicol. Environ. Health A 17(1) , 37-50, (1986)
The disposition of [14C]-2-bromo-4,6-dinitroaniline (BDNA) was studied in male F344 rats following oral or intravenous (iv) administration. The gastrointestinal absorption of BDNA was nearly complete ...