2-Methoxy-5-acetoxy-furanogermacr-1(10)-en-6-one

Names

[ Name ]:
2-Methoxy-5-acetoxy-furanogermacr-1(10)-en-6-one

[Synonym ]:
Cyclodeca[b]furan-4(5H)-one, 5-(acetyloxy)-6,7,8,11-tetrahydro-8-methoxy-3,6,10-trimethyl-, (5R,6R,8R,9E)-rel-

Biological Activity

[Description]:

2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one is a natural product found in the leaves and stem bark of M. glabra. 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one displays binding affinities with dipeptidyl peptidase-4 (DPP-4) and α-Amylase. 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one has potential antidiabetic activities[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Dipeptidyl Peptidase

Research Areas >> Metabolic Disease

[Target]

DPP-4[1], α-Amylase[1]

[References]

[1]. Alexandra Quek, et al. Identification of Dipeptidyl Peptidase-4 and α-Amylase Inhibitors from Melicope glabra (Blume) T. G. Hartley (Rutaceae) Using Liquid Chromatography Tandem Mass Spectrometry, In Vitro and In Silico Methods. Molecules. 2021 Jan; 26(1): 1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₂₄O₅

[ Molecular Weight ]:
320.38

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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