UniPR1447

Names

[ CAS No. ]:
1809170-68-0

[ Name ]:
UniPR1447

Biological Activity

[Description]:

UniPR1447 is Dual EphA2 and EphB2 antagonist, with an IC50 of 6.6 μM for EphA2−ephrin-A1 binding[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Ephrin Receptor

[References]

[1]. Lorenzo Guidetti, et al. Molecular Determinants of EphA2 and EphB2 Antagonism Enable the Design of Ligands with Improved Selectivity. J Chem Inf Model. 2023 Nov 1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₆H₅₀N₂O₄

[ Molecular Weight ]:
574.79

Related Compounds

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