BCR-ABL-IN-8

Names

[ CAS No. ]:
1808288-49-4

[ Name ]:
BCR-ABL-IN-8

Biological Activity

[Description]:

BCR-ABL-IN-8 (compound 26f) is a BCR-ABL inhibitor containing trimethoxy group[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Bcr-Abl

[References]

[1]. Liang X, et al. Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Leukemia. J Med Chem. 2016 Mar 10;59(5):1984-2004.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₀H₃₃N₇O₅

[ Molecular Weight ]:
571.63

Related Compounds

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