JP-153

Names

[ Name ]:
JP-153

Biological Activity

[Description]:

JP-153 (JP153) is a novel small molecule targets the Src-FAK-Paxillin signaling, inhibits Src-dependent phosphorylation of paxillin (Y118) and downstream activation of Akt (S473) in RECs; potently inhibits VEGF-induced proliferation and migration, inhibits retinal neovascularization in the murine oxygen-induced retinopathy model.

[References]

References 1. Toutounchian JJ, et al. Mol Pharmacol. 2017 Jan;91(1):1-13. View Related Products by Target Src

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₁₉NO₅

[ Molecular Weight ]:
365.385

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.