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Mz1

Names

[ CAS No. ]:
1797406-69-9

[ Name ]:
Mz1

Biological Activity

[Description]:

MZ 1 is a BRD4 protein degrader based on PROTAC technology.

[Related Catalog]:

Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain
Signaling Pathways >> PROTAC >> PROTAC
Research Areas >> Cancer

[Target]

BRD4[1]


[References]

[1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.


[Related Small Molecules]

(+)-JQ1 | GSK126 | Tazemetostat (EPZ-6438) | Birabresib (OTX015) | A 485 | Curcumin | ARV-771 | ARV-825 | I-BET762 | BI 2536 | GSK343 | C646 | 3-Deazaneplanocin A (hydrochloride) | I-BET151 | 666-15

Chemical & Physical Properties

[ Molecular Formula ]:
C49H60ClN9O8S2

[ Molecular Weight ]:
1002.64

[ Storage condition ]:
2-8℃

Related Compounds