LXR agonist 1

Names

[ CAS No. ]:
1779524-90-1

[ Name ]:
LXR agonist 1

Biological Activity

[Description]:

LXR (Liver X receptor) agonist 1 is potent LXR agonist with AC50s of 1.5 nM and 12 nM for LXR-α and LXR-β, respectively. LXR agonist 1 has the potential for the research of atherosclerosis[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Metabolic Enzyme/Protease >> LXR

[Target]

AC50: 1.5 nM (LXR-α); 12 nM (LXR-β)[1]


[In Vitro]

LXR agonist 1 (compound 3) shows binding affinities with AC50s of 1.5 nM and 12 nM for LXR-α and LXR-β, respectively[1].

[References]

[1]. Lim RK, et al. Targeted Delivery of LXR Agonist Using a Site-Specific Antibody-Drug Conjugate. Bioconjug Chem. 2015; 26(11):2216-22.

Chemical & Physical Properties

[ Molecular Formula ]:
C27H26F3N3O3S

[ Molecular Weight ]:
529.57

Related Compounds