β-Zearalanol-d4

Names

[ Name ]:
β-Zearalanol-d4

Biological Activity

[Description]:

β-Zearalanol-d4 is a deuterium labeled Beta-Zearalanol (HY-N6740）[1]. Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells[2]. Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid[3].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-246.

[2]. Yang F, et al. Melatonin alleviates β-zearalenol and HT-2 toxin-induced apoptosis and oxidative stress in bovine ovarian granulosa cells. Environ Toxicol Pharmacol. 2019 May;68:52-60.

[3]. Marin DE, et al. Cytotoxic and inflammatory effects of individual and combined exposure of HepG2 cells to zearalenone and its metabolites. Naunyn Schmiedebergs Arch Pharmacol. 2019 Aug;392(8):937-947.

Chemical & Physical Properties

[ Melting Point ]:
165 - 167°C

[ Molecular Formula ]:
C₁₈H₂₀D₄O₅

[ Molecular Weight ]:
324.40

[ Appearance of Characters ]:
Solid | White to Off-White

[ Storage condition ]:
Amber Vial, -20°C Freezer, Under Inert Atmosphere

[ Stability ]:
Light Sensitive

[ Water Solubility ]:
Acetone (Slightly), Methanol (Slightly)

Related Compounds

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