PAT1inh-B01

Names

[ Name ]:
PAT1inh-B01

Biological Activity

[Description]:

PAT1inh-B01 is a selective SLC26A6 inhibitor. PAT1inh-B01 inhibits PAT1 (a Cl-/HCO3- exchanger)-mediated anion exchange (IC50: 350 nM). PAT1inh-B01 blocks fluid absorption in small intestine. PAT1inh-B01 can be used for research of small intestinal hyposecretory disorders[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Cil O, et al. SLC26A6-selective inhibitor identified in a small-molecule screen blocks fluid absorption in small intestine. JCI Insight. 2021 Jun 8;6(11):e147699.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₁₈BrF₃N₆O₂

[ Molecular Weight ]:
535.32

Related Compounds

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