MAP4K4-IN-11e

Names

[ Name ]:
MAP4K4-IN-11e

Biological Activity

[Description]:

A potent, selective, ATP-competitive inhibitor of MAP4K4 with IC50 of 1.9 uM, without effect on other stress pathway related kinases; is active at much lower concentration in the cellular neurite outgrowth assay and may exhibit better pharmacokinetic properties.

[References]

References 1. Schröder P, et al. Angew Chem Int Ed Engl. 2015 Oct 12;54(42):12398-403. View Related Products by Target MAP4K

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₉NO₄

[ Molecular Weight ]:
301.342

Related Compounds

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