Trimethylsulfoxonium iodide
Names
[ CAS No. ]:
1774-47-6
[ Name ]:
Trimethylsulfoxonium iodide
[Synonym ]:
Trimethyl sulphoxonium ioidie
OS1&1&1 &&iodide
Trimethylsulfoxonium Iodide
Trimethyloxosulfonium iodide
trimethyl-oxo-sulfonium iodide
trimethyloxosulphonium iodide
MFCD00011899
trimethyl sulphoxonium iodide
dimethyloxosulfonium methylide
Corey-Chaykovsky reagent
EINECS 217-204-2
S,S,S-Trimethylsulfoxonium iodide
Sulfoxonium,trimethyl-,iodide
Chemical & Physical Properties
[ Melting Point ]:
208-212 °C (dec.)(lit.)
[ Molecular Formula ]:
C3H9IOS
[ Molecular Weight ]:
220.072
[ Exact Mass ]:
219.941864
[ PSA ]:
36.28000
[ Water Solubility ]:
15 g/L (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WS3585000
- CHEMICAL NAME :
- Sulfoxonium, trimethyl-, iodide
- CAS REGISTRY NUMBER :
- 1774-47-6
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C3-H9-O-S.I
- MOLECULAR WEIGHT :
- 220.08
- WISWESSER LINE NOTATION :
- OS1&1&1 &Q &I
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- IJRBA3 International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine. (Taylor & Francis Inc., 242 Cherry St., Philadelphia, PA 19106) V.1- 1959- Volume(issue)/page/year: 3,41,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04108
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
S37/39-S26
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
2
[ RTECS ]:
WS3585000
[ HS Code ]:
2930909090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2909199090
[ Summary ]:
2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%
Articles
Tetrahedron 50 , 9157, (1994)
Renin inhibitors containing C-termini derived from mercaptoheterocycles.
J. Med. Chem. 35 , 2103, (1992)
A series of transition-state analogues having heterocyclythio C-termini has been synthesized and evaluated for inhibition of human renin. Addition of mercaptoheterocycles to a chiral Boc-amino epoxide...
Tetrahedron 49 , 5067, (1993)