Methyl 2-bromobut-2-enoate
Names
[ CAS No. ]:
17642-18-1
[ Name ]:
Methyl 2-bromobut-2-enoate
[Synonym ]:
trans-2-Bromcrotonsaeure-methylester
METHYL A-BROMOCROTONATE
METHYL 2-BROMOCROTONATE
methyl bromo-crotonate
Einecs 241-627-1
methyl 2-bromobut-2-enoate
2-Bromo-2-butenoic acid methyl ester
Chemical & Physical Properties
[ Density]:
1.477g/cm3
[ Boiling Point ]:
165.8ºC at 760mmHg
[ Molecular Formula ]:
C5H7BrO2
[ Molecular Weight ]:
179.01200
[ Flash Point ]:
54.1ºC
[ Exact Mass ]:
177.96300
[ PSA ]:
26.30000
[ LogP ]:
1.45810
[ Vapour Pressure ]:
1.84mmHg at 25°C
[ Index of Refraction ]:
n20/D 1.486
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
36/37/38
[ Safety Phrases ]:
26-36
[ RIDADR ]:
NONH for all modes of transport
[ HS Code ]:
2916190090
Synthetic Route
Customs
[ HS Code ]: 2916190090
[ Summary ]:
2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%
Articles
J. Chem. Soc. Chem. Commun. , 413, (1976)
Enoate reductase-mediated preparation of methyl (S)-2-bromobutanoate, a useful key intermediate for the synthesis of chiral active pharmaceutical ingredients. Brenna E, et al.
Org. Process Res. Dev. 16(2) , 262-268, (2011)