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2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3,4-dihydro-3-[[(2,2,2-trifluoroethyl)thio]methyl]-, 1,1-dioxide

Names

[ CAS No. ]:
1764-85-8

[ Name ]:
2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3,4-dihydro-3-[[(2,2,2-trifluoroethyl)thio]methyl]-, 1,1-dioxide

[Synonym ]:
Epitizid
Epitizide
Epitizidum
P 2105
EPITHIAZIDE
Epithiazide [USAN]

Biological Activity

[Description]:

Epitizide, a benzothiadiazine, commonly found in combination Triamterene, is used to produce diuresis[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[References]

[1]. K Deventer, et al. Screening for 18 diuretics and probenecid in doping analysis by liquid chromatography-tandem mass spectrometry. Biomed Chromatogr. 2002 Dec;16(8):529-35.

Chemical & Physical Properties

[ Density]:
1.636g/cm3

[ Boiling Point ]:
586.6ºC at 760mmHg

[ Molecular Formula ]:
C10H11ClF3N3O4S3

[ Molecular Weight ]:
425.85500

[ Flash Point ]:
308.6ºC

[ Exact Mass ]:
424.95500

[ PSA ]:
160.42000

[ LogP ]:
4.64150

[ Vapour Pressure ]:
9.64E-14mmHg at 25°C

[ Index of Refraction ]:
1.566

Safety Information

[ HS Code ]:
2935009090

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Related Compounds