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cis-2,3-epoxybutane

Names

[ CAS No. ]:
1758-33-4

[ Name ]:
cis-2,3-epoxybutane

[Synonym ]:
cis-2-Butene oxide
cis-2-Butylene oxide
Butane,2,3-epoxy-,cis
Oxirane,2,3-dimethyl-,cis
cis-2,3-Epoxybutane
butane-2,3-epoxide
cis-2,3-Dimethyloxirane
trans-butene oxide
MFCD00005128
cis-2-Butene epoxide

Chemical & Physical Properties

[ Density]:
0.826

[ Boiling Point ]:
60-61ºC

[ Melting Point ]:
-1ºC

[ Molecular Formula ]:
C4H8O

[ Molecular Weight ]:
72.10570

[ Flash Point ]:
-21.7ºC

[ Exact Mass ]:
72.05750

[ PSA ]:
12.53000

[ LogP ]:
0.79360

[ Vapour Pressure ]:
239mmHg at 25°C

[ Index of Refraction ]:
1.382-1.384

[ Storage condition ]:
Flammables area

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EK3855020
CHEMICAL NAME :
Butane, 2,3-epoxy-, cis-
CAS REGISTRY NUMBER :
1758-33-4
BEILSTEIN REFERENCE NO. :
0079770
LAST UPDATED :
199710
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C4-H8-O
MOLECULAR WEIGHT :
72.12

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
12500 mol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 249,55,1991

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H315-H319-H335

[ Precautionary Statements ]:
P210-P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
F:Flammable;Xn:Harmful;

[ Risk Phrases ]:
R11;R20/21/22;R36/37/38

[ Safety Phrases ]:
S16-S26-S36/37/39

[ RIDADR ]:
UN 3271

[ WGK Germany ]:
3

[ RTECS ]:
EK3855020

[ Packaging Group ]:
II

[ Hazard Class ]:
3

Articles

Non-mutagenicity of 2-methyl-2,3-epoxybutane and factors influencing the mutagenicity of 2,3-epoxybutane.

J. Appl. Toxicol. 2(6) , 284-8, (1982)

The compound 2,3-epoxybutane (2,3-EB) is a direct mutagen for the base-pair-substitution-sensitive strains TA 1530, TA 1535 and TA 100, in the absence and in the presence of metabolic activation by li...

Assessing the potential for diol and hydroxy sulfate ester formation from the reaction of epoxides in tropospheric aerosols.

Environ. Sci. Technol. 43(5) , 1386-92, (2009)

Polyols and sulfate esters have recently been identified in the secondary organic aerosol (SOA) formed in the photooxidation of biogenic hydrocarbons both in the laboratory and under ambient atmospher...

Increase of 2,3-epoxybutane mutagenicity by glutathione-S-transferases.

Toxicol. Lett. 21(3) , 255-62, (1984)

The mutagenicity of 2,3- epoxybutane (2,3-EB) towards Salmonella FFphimurium TA1530 is increased by rat liver S9 mix. This enhancement can be induced by Aroclor 1254 (ARO) or phenobarbitone (PB) pretr...


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