methylcapsaicin

Names

[ Name ]:
methylcapsaicin

[Synonym ]:
Methylcapsaicin
markiertes Capsaicin
O-Methyl-capsaicin

Biological Activity

[Description]:

TRPV1 activator-2 (compound 9), a capsaicin head analog, makes specific interactions with channel residues at the lipid-water[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel

Research Areas >> Metabolic Disease

[References]

[1]. Fan Yang, et al. Structural mechanism underlying capsaicin binding and activation of the TRPV1 ion channel. Nat Chem Biol. 2015 Jul;11(7):518-524.

Chemical & Physical Properties

[ Density]:
1.03g/cm3

[ Boiling Point ]:
515.9ºC at 760mmHg

[ Molecular Formula ]:
C₁₉H₂₉NO₃

[ Molecular Weight ]:
319.43800

[ Flash Point ]:
265.8ºC

[ Exact Mass ]:
319.21500

[ PSA ]:
58.56000

[ LogP ]:
4.42650

[ Vapour Pressure ]:
2.91E-11mmHg at 25°C

[ Index of Refraction ]:
1.52

Safety Information

[ HS Code ]:
2924299090

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%