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CDD3505

Names

[ CAS No. ]:
173865-33-3

[ Name ]:
CDD3505

[Synonym ]:
4-Nitro-1-trityl-1H-imidazole
1H-Imidazole, 4-nitro-1-(triphenylmethyl)-
1-trityl-4-nitroimidazole

Biological Activity

[Description]:

CDD3505 is used for elevating high density lipoprotein cholesterol (HDL) by inducing hepatic cytochrome P450IIIA (CYP3A) activity.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450
Research Areas >> Metabolic Disease

[In Vitro]

CDD3505 specifically induces hepatic cytochrome P450IIIA produces significant increases in HDL cholesterol[1].

[References]

[1]. Method for increasing HDL cholesterol levels using heteroaromatic phenylmethanes. United States Patent 6103733


[Related Small Molecules]

Talarozole | Apigenin | Cobicistat (GS-9350) | Ginsenoside Compound K | Gemfibrozil | Isavuconazole | Naringin | Orteronel | Proadifen hydrochloride | Galangin | Galeterone | Tetrahydrocurcumin | 1-Aminobenzotriazole | Furafylline | Ginsenoside F1

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
515.7±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C22H17N3O2

[ Molecular Weight ]:
355.389

[ Flash Point ]:
265.7±28.7 °C

[ Exact Mass ]:
355.132080

[ LogP ]:
5.02

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.635

[ Storage condition ]:
2-8℃