7-[[2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-3,5-dihydroxy-2-(4-hydroxyphenyl)-4H-benzopyran-4-one

Names

[ Name ]:
7-[[2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-3,5-dihydroxy-2-(4-hydroxyphenyl)-4H-benzopyran-4-one

[Synonym ]:
4'-O-Methylkaempferol
3,5,4'-trihydroxy-7-methoxyflavanone
4'-Methoxy-3,5,7-trihydroxyflavone
Kaempferide
Kaempferid
kaempferol 4'-methyl ether
Kaempferol 7-O-neohesperidoside
kaempferol 7-neohesperidoside
4'-Methylkaempferol
kaempferol 7-O-neohesperidoside
3,5,7-trihydroxy-4'-methoxyflavone
kaempferol 7-neohsperidoside
5,7-dihydroxy-4'-methoxyflavonol

Biological Activity

[Description]:

Kaempferol 7-O-neohesperidoside is a ?avonoid glycoside that can be isolated from Litchi chinensis. Kaempferol 7-O-neohesperidoside exhibits significant cytotoxic activity against A549, LAC, Hep-G2, and HeLa cell lines with IC50s of 0.53, 7.93, 0.020, and 0.051 μM, respectively[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Xu X, et al. Flavonoid Glycosides from the Seeds of Litchi chinensis. J Agric Food Chem. 2011 Feb 23;59(4):1205-9.

Chemical & Physical Properties

[ Density]:
1.76g/cm3

[ Boiling Point ]:
934.7ºC at 760mmHg

[ Molecular Formula ]:
C₂₇H₃₀O₁₅

[ Molecular Weight ]:
594.51800

[ Flash Point ]:
310.4ºC

[ Exact Mass ]:
594.15800

[ PSA ]:
249.20000

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.744

[ Storage condition ]:
20°C

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Flavonoid Glycosides from the Seeds of Litchi chinensis.

J. Agric. Food Chem. 59 , 1205-1209, (2011)

Seven flavonoid glycosides, including one new (1) and five previously uncharacterized (3-7), were obtained from the seeds of lychee ( Litchi chinensis Sonn. cv. Heiye) by means of repetitive column ch...

A general analytical strategy for the characterization of phenolic compounds in fruit juices by high-performance liquid chromatography with diode array detection coupled to electrospray ionization and triple quadrupole mass spectrometry.

J. Chromatogr. A. 1216 , 5398-5415, (2009)

In the present study, a methodology based on liquid chromatography with diode array detection (HPLC/DAD) coupled to an electrospray ionization (ESI) interface and a triple quadrupole mass spectrometer...

NMR studies of a plant flavonoid--DNA oligonucleotide complex.

Acta Chem. Scand. 47(7) , 658-62, (1993)

A structural model of the solution complex between a flavonoid and a DNA dodecamer containing the E. coli wild-type lac promoter sequence (TATGTT) was obtained using simulated annealing for refinement...

Related Compounds

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