Tazettine,6a-deoxy-8-hydroxy-, hydrochloride, (6ab,8b)- (9CI)
Names
[ CAS No. ]:
17322-85-9
[ Name ]:
Tazettine,6a-deoxy-8-hydroxy-, hydrochloride, (6ab,8b)- (9CI)
[Synonym ]:
isotazettine,hydrochloride
(3s,4as,6ar,8r,13bs)-3-methoxy-5-methyl-3,4,4a,5,6,6a-hexahydro-8h-[1,3]dioxolo[6,7]isochromeno[3,4-c]indol-8-ol
Tazettine,6a-deoxy-8-hydroxy-,(6abeta,8beta)
(+)-pretazettine
Pretazettin
isotazettine
pratazettine hydrochloride
Pretazettin-hydrochlorid
Chemical & Physical Properties
[ Boiling Point ]:
499.6ºC at 760mmHg
[ Molecular Formula ]:
C18H22ClNO5
[ Molecular Weight ]:
367.82400
[ Flash Point ]:
255.9ºC
[ Exact Mass ]:
367.11900
[ PSA ]:
60.39000
[ LogP ]:
2.07160
[ Vapour Pressure ]:
8.45E-11mmHg at 25°C
[ Index of Refraction ]:
1.656
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TU7500000
- CHEMICAL NAME :
- Pretazettine, hydrochloride
- CAS REGISTRY NUMBER :
- 17322-85-9
- LAST UPDATED :
- 198207
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C18-H21-N-O5.Cl-H
- MOLECULAR WEIGHT :
- 367.86
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 47 mg/kg
- TOXIC EFFECTS :
- Cardiac - pulse rate Vascular - BP lowering not characterized in autonomic section
- REFERENCE :
- PWPSA8 Proceedings of the Western Pharmacology Society. (Univ. of California Dept. of Pharmacology, Los Angeles, CA 90024) V.1- 1958- Volume(issue)/page/year: 24,259,1981