3beta,4beta-Dihydroxycholest-5-ene

Names

[ Name ]:
3beta,4beta-Dihydroxycholest-5-ene

[Synonym ]:
4beta-hydroxycholesterol
Cholest-5-ene-3beta,4beta-diol
Cholest-5-ene-3β,4β-diol
4-Hydroxy Cholesterol
cholest-5-ene-3,4-diol
(3β,4β)-Cholest-5-ene-3,4-diol
4β-hydroxy-cholesterol
4β-Hydroxycholesterol
Cholest-5-ene-3,4-diol, (3β,4β)-
cholest-5-en-3β,4β-diol
4-β-HYDROXYCHOLESTEROL

Biological Activity

[Description]:

4β-hydroxy Cholesterol is a major oxysterol cholesterol metabolite and a precursor in the synthesis of bile acids that is found in human circulation[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Granchi C, Rizzolio F, Bordoni V, Caligiuri I, Manera C, Macchia M, Minutolo F, Martinelli A, Giordano A, Tuccinardi T. 4-Aryliden-2-methyloxazol-5(4H)-one as a new scaffold for selective reversible MAGL inhibitors. J Enzyme Inhib Med Chem. 2016;31(1):137-46.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
500.2±30.0 °C at 760 mmHg

[ Melting Point ]:
175-176 °C

[ Molecular Formula ]:
C₂₇H₄₆O₂

[ Molecular Weight ]:
402.653

[ Flash Point ]:
206.7±19.2 °C

[ Exact Mass ]:
402.349792

[ PSA ]:
40.46000

[ LogP ]:
8.80

[ Vapour Pressure ]:
0.0±2.9 mmHg at 25°C

[ Index of Refraction ]:
1.536

[ Storage condition ]:
2-8°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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