α-tocotrienol
Names
[ CAS No. ]:
1721-51-3
[ Name ]:
α-tocotrienol
[Synonym ]:
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-2H-1-benzopyran-6-ol
alpha-tocotrienol
D-α-Tocotrienol
2,5,7,8-Tetramethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatri en-1-yl]-6-chromanol
Chemical & Physical Properties
[ Density]:
0.96g/cm3
[ Boiling Point ]:
541.7ºC at 760mmHg
[ Molecular Formula ]:
C29H44O2
[ Molecular Weight ]:
424.65800
[ Flash Point ]:
222.3ºC
[ Exact Mass ]:
424.33400
[ PSA ]:
29.46000
[ LogP ]:
8.60050
[ Vapour Pressure ]:
2.39E-12mmHg at 25°C
[ Index of Refraction ]:
1.522
MSDS
Safety Information
[ RIDADR ]:
NONH for all modes of transport
Articles
Cell Prolif. 46(2) , 203-13, (2013)
Tocotrienols and tocopherols are members of the vitamin E family, with similar structures; however, only tocotrienols have been reported to achieve potent anti-cancer effects. The study described here...
Tissue distribution of vitamin E metabolites in rats after oral administration of tocopherol or tocotrienol.J. Nutr. Sci. Vitaminol. 57(5) , 326-32, (2011)
We previously found that 2,7,8-trimethyl-2(2'-carboxyethyl)-6-hydroxychroman (_CEHC), a metabolite of the vitamin E isoforms _-tocopherol or _-tocotrienol, accumulated in the rat small intestine. The ...
δ- and γ-tocotrienols induce classical ultrastructural apoptotic changes in human T lymphoblastic leukemic cells.Microsc. Microanal. 18(3) , 462-9, (2012)
Tocotrienols are isomers of the vitamin E family, which have been reported to exert cytotoxic effects in various cancer cells. Although there have been some reports on the effects of tocotrienols in l...