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α-tocotrienol

Names

[ CAS No. ]:
1721-51-3

[ Name ]:
α-tocotrienol

[Synonym ]:
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-2H-1-benzopyran-6-ol
alpha-tocotrienol
D-α-Tocotrienol
2,5,7,8-Tetramethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatri en-1-yl]-6-chromanol

Chemical & Physical Properties

[ Density]:
0.96g/cm3

[ Boiling Point ]:
541.7ºC at 760mmHg

[ Molecular Formula ]:
C29H44O2

[ Molecular Weight ]:
424.65800

[ Flash Point ]:
222.3ºC

[ Exact Mass ]:
424.33400

[ PSA ]:
29.46000

[ LogP ]:
8.60050

[ Vapour Pressure ]:
2.39E-12mmHg at 25°C

[ Index of Refraction ]:
1.522

MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

Tocotrienols promote apoptosis in human breast cancer cells by inducing poly(ADP-ribose) polymerase cleavage and inhibiting nuclear factor kappa-B activity.

Cell Prolif. 46(2) , 203-13, (2013)

Tocotrienols and tocopherols are members of the vitamin E family, with similar structures; however, only tocotrienols have been reported to achieve potent anti-cancer effects. The study described here...

Tissue distribution of vitamin E metabolites in rats after oral administration of tocopherol or tocotrienol.

J. Nutr. Sci. Vitaminol. 57(5) , 326-32, (2011)

We previously found that 2,7,8-trimethyl-2(2'-carboxyethyl)-6-hydroxychroman (_CEHC), a metabolite of the vitamin E isoforms _-tocopherol or _-tocotrienol, accumulated in the rat small intestine. The ...

δ- and γ-tocotrienols induce classical ultrastructural apoptotic changes in human T lymphoblastic leukemic cells.

Microsc. Microanal. 18(3) , 462-9, (2012)

Tocotrienols are isomers of the vitamin E family, which have been reported to exert cytotoxic effects in various cancer cells. Although there have been some reports on the effects of tocotrienols in l...


More Articles


Related Compounds

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