Isopropyl nitrate
Names
[ CAS No. ]:
1712-64-7
[ Name ]:
Isopropyl nitrate
[Synonym ]:
Nitric acid, 1-methylethyl ester
propan-2-yl nitrate
Nitric acid isopropyl
2-nitrooxypropane
2-Propanol nitrate
(CH3)2CHONO2
Isopropyl nitrate
isopriopyl nitrate
1-methylethyl nitrate
Propan-2-ol nitrate
propane-2-nitrate
EINECS 216-983-6
MFCD00007041
2-propyl nitrate
i-propyl nitrate
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
99.6±8.0 °C at 760 mmHg
[ Molecular Formula ]:
C3H7NO3
[ Molecular Weight ]:
105.093
[ Flash Point ]:
12.8±0.0 °C
[ Exact Mass ]:
105.042595
[ PSA ]:
55.05000
[ LogP ]:
1.43
[ Vapour Pressure ]:
43.7±0.2 mmHg at 25°C
[ Index of Refraction ]:
1.400
[ Stability ]:
Stability Highly flammable. Incompatible with strong reducing agents, strong acids, finely powdered metals, tin chloride, boron trifluoride.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QU8930000
- CHEMICAL NAME :
- Nitric acid, isopropyl ester
- CAS REGISTRY NUMBER :
- 1712-64-7
- BEILSTEIN REFERENCE NO. :
- 1701405
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C3-H7-N-O3
- MOLECULAR WEIGHT :
- 105.11
- WISWESSER LINE NOTATION :
- WNOY1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 29 gm/m3/2H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 33,110,1970
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 65 gm/m3/2H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,78,1982 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 5 mg/m3 JAN 1993 OEL-SWEDEN:TWA 10 ppm (45 mg/m3);STEL 15 ppm (70 mg/m3) JAN 1993
Safety Information
[ Symbol ]:
GHS02
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H225
[ Precautionary Statements ]:
P210
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
O:Oxidizingagent;F:Flammable;Xn:Harmful;
[ Risk Phrases ]:
R5;R8;R11;R20
[ Safety Phrases ]:
S16-S17-S33-S7/9
[ RIDADR ]:
UN 1222 3/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
QU8930000
[ Packaging Group ]:
II
[ Hazard Class ]:
3.1
[ HS Code ]:
2920909090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2920909090
[ Summary ]:
2920909090 esters of other inorganic acids of non-metals (excluding esters of hydrogen halides) and their salts; their halogenated, sulphonated, nitrated or nitrosated derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
Articles
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 58(12) , 2571-80, (2002)
Raman and infrared spectra of isopropyl nitrate and isobutyl nitrate are reported. These spectra are used in combination with computational studies employing density functional theory at the B3-LYP/6-...
Biological monitoring of isopropyl nitrate.Toxicol. Lett. 47(2) , 205-11, (1989)
Four healthy men were exposed to an isopropyl nitrate (IPN) concentration of 45.8 mg/m3 for 60 min. The IPN in the expired air, blood and urine of volunteers was analysed by gas chromatography. The lo...
Poppers-associated retinal toxicity.N. Engl. J. Med. 363(16) , 1583-5, (2010)