GR 196429

Names

[ Name ]:
GR 196429

Biological Activity

[Description]:

GR 196429 is a melatonin receptor agonist with some selectivity for the MT1 subtype. GR-196429 produces both sleep-promoting effects and alterations of circadian rhythm, as well as stimulating melatonin release in mice.

[References]

1. Hardeland R. Melatonin and Synthetic Melatoninergic Agonists in Psychiatric and Age-associated Disorders: Successful and Unsuccessful Approaches. Curr Pharm Des. 2016;22(8):1086-101. Review. PubMed PMID: 25248806.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₁₈N₂O₂

[ Molecular Weight ]:
246.3