curcolone

Names

[ Name ]:
curcolone

[Synonym ]:
Curculone
(8S,8aS)-8-Hydroxy-3,5,8a-trimethyl-7,8,8a,9-tetrahydro-6H-naphtho[2,3-b]furan-4-one
curculone
Nehipetol

Biological Activity

[Description]:

Curcolone is a sesquiterpenoid that inhibits collagen-induced or arachidonic acid (AA)-induced platelet aggregation[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

[References]

[1]. Jih-Jung Chen, et al. New Sesquiterpenoids and Anti-Platelet Aggregation Constituents from the Rhizomes of Curcuma zedoaria. Molecules. 2016 Oct 17;21(10):1385.

Chemical & Physical Properties

[ Density]:
1.21±0.1 g/cm3

[ Melting Point ]:
139.0-139.5 ºC

[ Molecular Formula ]:
C₁₅H₁₈O₃

[ Molecular Weight ]:
246.30200

[ Exact Mass ]:
246.12600

[ PSA ]:
50.44000

[ LogP ]:
2.80430

[ Water Solubility ]:
Very slightly soluble (0.52 g/L) (25 ºC)

Related Compounds

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