amidepsine A

Names

[ Name ]:
amidepsine A

[Synonym ]:
N-[4-({4-[(2,4-Dimethoxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methylbenzoyl}oxy)-2-hydroxy-6-methylbenzoyl]alanine
Benzoic acid, 4-[(2,4-dimethoxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methyl-, 4-[[(1-carboxyethyl)amino]carbonyl]-3-hydroxy-5-methylphenyl ester

Biological Activity

[Description]:

Amidepsine A is a fungal metabolite isolated from the culture broth of Humicola sp. FO-2942 that inhibits Diacylglycerol acyltransferases (DGAT) activity[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Tomoda H, et al. Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. I. Production, isolation and biological properties. J Antibiot (Tokyo). 1995 Sep;48(9):937-41.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
773.3±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₉H₂₉NO₁₁

[ Molecular Weight ]:
567.541

[ Flash Point ]:
421.4±32.9 °C

[ Exact Mass ]:
567.174072

[ LogP ]:
5.72

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.613

Related Compounds

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