Roridin E
Names
[ CAS No. ]:
16891-85-3
[ Name ]:
Roridin E
[Synonym ]:
Verrucarin A,2',3'-didehydro-7'-deoxo-2'-deoxy-7'-(1-hydroxyethyl)-,(2'E,7'R(R))
Verrucarin A,2',3'-didehydro-7'-deoxo-2'-deoxy-7'-((1R)-1-hydroxyethyl)-,(2'E,7'R)
roridinee
(2'E,7'R)-2',3'-Didehydro-7'-deoxo-2'-deoxy-7'-[(R)-1-hydroxyethyl]verrucarin A
Chemical & Physical Properties
[ Density]:
1.26g/cm3
[ Boiling Point ]:
740.3ºC at 760 mmHg
[ Molecular Formula ]:
C29H38O8
[ Molecular Weight ]:
514.60700
[ Flash Point ]:
243.4ºC
[ Exact Mass ]:
514.25700
[ PSA ]:
103.82000
[ LogP ]:
3.34270
[ Vapour Pressure ]:
2.67E-25mmHg at 25°C
[ Index of Refraction ]:
1.58
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YX9821500
- CHEMICAL NAME :
- Verrucarin A, 2',3'-didehydro-7'-deoxo-2'-deoxy-7'-(1-hydroxyethyl) -, (2'E,7'R(R))-
- CAS REGISTRY NUMBER :
- 16891-85-3
- LAST UPDATED :
- 198611
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C29-H38-O8
- MOLECULAR WEIGHT :
- 514.67
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 55 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - muscle contraction or spasticity
- REFERENCE :
- TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 23,731,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - muscle contraction or spasticity
- REFERENCE :
- TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 23,731,1985
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 17300 ug/kg
- TOXIC EFFECTS :
- Gastrointestinal - ulceration or bleeding from large intestine Gastrointestinal - hypermotility, diarrhea
- REFERENCE :
- TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 23,731,1985