RVG-9R trifluoroacetate salt

Names

[ Name ]:
RVG-9R trifluoroacetate salt

Biological Activity

[Description]:

Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R), a chimeric peptide consisting of 29 amino acids, is synthesized by adding nona-arginine motif to the carboxy terminus of RVG (rabies virus glycoprotein). Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R) is positively charged and able to bind negatively charged nucleic acids via charge interaction[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

[References]

[1]. Rassu G, et al. Nose-to-brain delivery of BACE1 siRNA loaded in solid lipid nanoparticles for Alzheimer's therapy. Colloids Surf B Biointerfaces. 2017 Apr 1;152:296-301.

[2]. Margus H, et al. Cell-penetrating peptides as versatile vehicles for oligonucleotide delivery. Mol Ther. 2012 Mar;20(3):525-33.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀₁H₃₃₄N₈₂O₅₅S₂

[ Molecular Weight ]:
4843.51

Related Compounds

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