2-Chloro-5-nitrobenzonitrile
Names
[ CAS No. ]:
16588-02-6
[ Name ]:
2-Chloro-5-nitrobenzonitrile
[Synonym ]:
2-Chlor-5-nitrobenzolcarbonitril
2-chlor-5-nitrobenzonitrile
2-Chloro-5-nitrobenzenenitrile
3-cyano-4-chloronitrobenzene
MFCD00007292
4-chloro-3-cyanonitrobenzene
1-CHLORO-2-CYANO-4-NITROBENZENE
2-chlor-5-nitrobenzonitril
2-chloro-5-nitro-benzonitrile
2-cyano-4-nitrochlorobenzene
EINECS 240-643-6
2-chloro-5-nitro-benzonitril
Benzonitrile, 2-chloro-5-nitro-
4-Chloro-3-cyano-1-nitrobenzene
5-Nitro-2-chlorobenzonitrile
2-chloro-3-cyano-5-nitrobenzene
BENZONITRILE,2-CHLORO-5-NITRO
2-Chloro-5-nitrobenzonitrile
2-Chloro-1-cyano-5-nitrobenzene
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
300.3±27.0 °C at 760 mmHg
[ Melting Point ]:
105-108ºC
[ Molecular Formula ]:
C7H3ClN2O2
[ Molecular Weight ]:
182.564
[ Flash Point ]:
135.4±23.7 °C
[ Exact Mass ]:
181.988312
[ PSA ]:
69.61000
[ LogP ]:
1.79
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.599
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DI3040000
- CHEMICAL NAME :
- Benzonitrile, 2-chloro-5-nitro-
- CAS REGISTRY NUMBER :
- 16588-02-6
- LAST UPDATED :
- 199209
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C7-H3-Cl-N2-O2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3200 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- ZAARAM Zentralblatt fuer Arbeitsmedizin und Arbeitsschutz. (Darmstadt, Fed. Rep. Ger.) V.1-25, 1951-75. Volume(issue)/page/year: 19,225,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 240 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- ZAARAM Zentralblatt fuer Arbeitsmedizin und Arbeitsschutz. (Darmstadt, Fed. Rep. Ger.) V.1-25, 1951-75. Volume(issue)/page/year: 19,225,1969
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H312 + H332-H315-H319-H335
[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S37/39
[ RIDADR ]:
UN 3276
[ WGK Germany ]:
3
[ RTECS ]:
DI3040000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Xenobiotica 26(2) , 143-55, (1996)
1. Four different rat glutathione S-transferase (GST) isoenzymes, belonging to three different classes, were examined for their GSH conjugating capacity towards 11 2-substituted 1-chloro-4-nitrobenzen...
Online biochemical detection of glutathione-S-transferase P1-specific inhibitors in complex mixtures.J. Biomol. Screen. 12(3) , 396-405, (2007)
A high-resolution screening (HRS) technology is described, which couples 2 parallel enzyme affinity detection (EAD) systems for substrates and inhibitors of rat cytosolic glutathione-S-transferases (c...