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orelabrutinib

Names

[ CAS No. ]:
1655504-04-3

[ Name ]:
orelabrutinib

Biological Activity

[Description]:

Orelabrutinib (ICP-022) is a potent, orally active, and irreversible Bruton's tyrosine kinase (BTK) inhibitor. Orelabrutinib has the potential for B-cell malignancies treatment[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk

[References]

[1]. Wei Xu, et al. Safety, Tolerability and Efficacy of Orelabrutinib, Once a Day, to Treat Chinese Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Cell Leukemia. Blood (2019) 134 (Supplement_1): 4319.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H25N3O3

[ Molecular Weight ]:
427.50

Related Compounds