1,3-Benzodioxole-5-ethanamine,hydrochloride (1:1)
Names
[ CAS No. ]:
1653-64-1
[ Name ]:
1,3-Benzodioxole-5-ethanamine,hydrochloride (1:1)
[Synonym ]:
MFCD00035193
2-(1,3-Benzodioxol-5-yl)ethanaminium
1,3-Benzodioxole-5-ethanaminium
2-(1,3-benzodioxol-5-yl)ethanamine,hydrochloride
2-[3,4-(Methylenedioxy)phenyl]ethylamine hydrochloride
Chemical & Physical Properties
[ Density]:
1.225
[ Boiling Point ]:
166℃
[ Melting Point ]:
216-218 °C(lit.)
[ Molecular Formula ]:
C9H12NO2
[ Molecular Weight ]:
201.65000
[ Flash Point ]:
129.8ºC
[ Exact Mass ]:
201.05600
[ PSA ]:
44.48000
[ LogP ]:
2.41880
[ Vapour Pressure ]:
0.00543mmHg at 25°C
[ Index of Refraction ]:
1.5620
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SH9710000
- CHEMICAL NAME :
- Phenethylamine, 3,4-methylenedioxy-, hydrochloride
- CAS REGISTRY NUMBER :
- 1653-64-1
- LAST UPDATED :
- 197901
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C9-H11-N-O2.Cl-H
- MOLECULAR WEIGHT :
- 201.67
- WISWESSER LINE NOTATION :
- T56 BO DO CHJ G2Z &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 55 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 176 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 28 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 45 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 245 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
T+: Very toxic;Xi: Irritant;
[ Risk Phrases ]:
R26/27/28
[ Safety Phrases ]:
S22-S26-S36/37/39-S45-S24/25
[ RIDADR ]:
UN 2811 6.1/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
SH9710000
[ HS Code ]:
2932999099
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2932999099
[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
J. Med. Chem. 19(7) , 876-82, (1976)
Synthesis of a series of thienylethanolamines having varying substituents on the thiophene ring and on the nitrogen atom is described using the general procedure reported earlier. In the determination...
An aryne route to laureline, and related topics. Gibson MS, et al.J. Chem. Soc. Sect. C 16 , 2234-2238, (1970)
Determination of paramethoxyamphetamine and other amphetamine-related designer drugs by liquid chromatography/sonic spray ionization mass spectrometry.
Rapid Commun. Mass Spectrom. 16(9) , 865-70, (2002)
Paramethoxyamphetamine (PMA) is an amphetamine-like designer drug that has emerged recently on the European illicit drug market. This drug has a wicked reputation, as a number of lethal intoxications ...