Cryptosporioptide A

Names

[ CAS No. ]:
1647101-05-0

[ Name ]:
Cryptosporioptide A

Biological Activity

[Description]:

Cryptosporioptide A (Compound 3) is a pigment protein tyrosine phosphatase inhibitor derived from the insect-parasitic fungus Cordyceps gracilioides. Cryptosporioptide A inhibits PTP1B, SHP2, CDC25B, LAR and SHP1 enzymes with IC50 of 7.3, 5.7, 7.6, >50, 4.9 μg/mL, respectively[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase
Research Areas >> Metabolic Disease

[References]

[1]. Wei PY, et al. Three new pigment protein tyrosine phosphatases inhibitors from the insect parasite fungus Cordyceps gracilioides: terreusinone A, pinophilin C and cryptosporioptide A. Molecules. 2015 Apr 2;20(4):5825-34.  

Chemical & Physical Properties

[ Molecular Formula ]:
C18H17NO10

[ Molecular Weight ]:
407.33