Tabituximab

Names

[ CAS No. ]:
1644134-10-0

[ Name ]:
Tabituximab

Biological Activity

[Description]:

Tabituximab (OTSA101) is a humanized monoclonal antibody against frizzled class receptor 10 (FZD10)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[Target]

FZD10[1]

[In Vitro]

非放射标记的 Tabituximab (OTSA101) 抗体对滑膜肉瘤细胞生长只有较弱的拮抗活性[1]。

[In Vivo]

Yttrium 90 放射标记的 OTSA101 (OTSA101-DTPA-90Y) 在小鼠异种移植模型静脉单次注射后显示出显著的抗肿瘤活性[1]。

[References]

[1]. Blagodatski A, et al. Targeting the Wnt pathways for therapies. Mol Cell Ther. 2014 Sep 11;2:28.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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