Pinatuzumab

Names

[ Name ]:
Pinatuzumab

Biological Activity

[Description]:

Pinatuzumab is a CD22 monoclonal antibody. Pinatuzumab targets the cell-surface antigen CD22. Pinatuzumab can be used for synthesis of antibody drug conjugates (ADCs) to research several diseases including non-Hodgkin lymphoma (NHL)[1][2].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cytoskeleton >> Integrin

[References]

[1]. June Ereño-Orbea, et al. Structural Basis of Enhanced Crystallizability Induced by a Molecular Chaperone for Antibody Antigen-Binding Fragments. J Mol Biol. 2018 Feb 2;430(3):322-336

[2]. Shang-Fan Yu, et al. An Anti-CD22- seco-CBI-Dimer Antibody-Drug Conjugate (ADC) for the Treatment of Non-Hodgkin Lymphoma That Provides a Longer Duration of Response than Auristatin-Based ADCs in Preclinical Models. Mol Cancer Ther. 2021 Feb;20(2):340-346.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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