Longiferone B

Names

[ Name ]:
Longiferone B

[Synonym ]:
(3R,3aS,8aR)-3-Isopropenyl-6,8a-dimethyl-2,3,3a,4,8,8a-hexahydro-5(1H)-azulenone
5(1H)-Azulenone, 2,3,3a,4,8,8a-hexahydro-6,8a-dimethyl-3-(1-methylethenyl)-, (3R,3aS,8aR)-

Biological Activity

[Description]:

Longiferone B is a daucane sesquiterpene, that can be isolated from Boesenbergia longiflora rhizomes. Longiferone B shows anti-inflammatory activity against NO release with an IC50 of 21.0 μM. Longiferone B also suppresses the iNOS and COX-2 mRNA expression[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> NO Synthase

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Immunology/Inflammation >> COX

[Target]

iNOS

COX-2

[References]

[1]. Sudsai T, et al. Anti-inflammatory activity of compounds from Boesenbergia longiflora rhizomes. J Ethnopharmacol. 2014 Jun 11;154(2):453-61.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
309.5±22.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₅H₂₂O

[ Molecular Weight ]:
218.33

[ Flash Point ]:
138.7±13.2 °C

[ Exact Mass ]:
218.167068

[ LogP ]:
4.16

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.500

[ Storage condition ]:
2-8℃

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.