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Kaempferol-3-O-(6''-O-cis-coumaryl)glucoside

Names

[ CAS No. ]:
163956-16-9

[ Name ]:
Kaempferol-3-O-(6''-O-cis-coumaryl)glucoside

[Synonym ]:
4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[[6-O-[(2Z)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]-β-D-glucopyranosyl]oxy]-
Tribuloside
5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 6-O-[(2Z)-3-(4-hydroxyphenyl)-2-propenoyl]-β-D-glucopyranoside
5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 6-O-[(2Z)-3-(4-hydroxyphenyl)prop-2-enoyl]-β-D-glucopyranoside
cis-Tiliroside
Kaempferol 3-beta-D-(6-O-cis-p-coumarylglucopyranoside)
Kaempferol-3-O-(6''-O-cis-coumaryl)glucoside

Biological Activity

[Description]:

cis-Tiliroside, a kaempferol derivative, is a flavonoid glycoside. cis-Tiliroside exhibits better cytotoxic activity than trans-Tiliroside in A549 cell line[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[In Vitro]

cis-Tiliroside has CC50s of 68.05 μg/mL and 18.82 μg/mL for A549 cell line in 24 h or 48 h, respectively. trans-Tiliroside has CC50s of 149.90 μg/mL and 144.74 μg/mL for A549 cell line in 24 h or 48 h, respectively[1]. cis-Tiliroside exhibits better cytotoxic activity than kaempferol, which has CC50s of 129.15 μg/mL and 113.48 μg/mL for A549 cell line in 24 h or 48 h, respectively[1].

[References]

[1]. Chi-Ren Liao, et al. Studies on cytotoxic constituents from the leaves of Elaeagnus oldhamii Maxim. in non-small cell lung cancer A549 cells. Molecules. 2014 Jul 4;19(7):9515-34.

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
943.9±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C30H26O13

[ Molecular Weight ]:
594.52

[ Flash Point ]:
311.9±27.8 °C

[ Exact Mass ]:
594.137329

[ LogP ]:
3.83

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.759

Related Compounds