Burimamide oxalate

Names

[ Name ]:
Burimamide oxalate

[Synonym ]:
1-[4-(1H-Imidazol-4-yl)butyl]-3-methylthiourea ethanedioate (1:1)
Thiourea, N-[4-(1H-imidazol-5-yl)butyl]-N'-methyl-, ethanedioate (1:1)

Biological Activity

[Description]:

Burimamide oxalate is a potent dual H3/H2 receptor antagonist with Ki of 0.07 and 7.8 uM, respectively; shows weak affinity for H1, and has antinociceptive effects in vivo.

[References]

References 1. Wyllie JH, et al. Lancet. 1972 Nov 25;2(7787):1117-20. 2. Ambache N, et al. Br J Pharmacol. 1973 Jun;48(2):362P-363P. 3. Capurro N, et al. Br J Pharmacol. 1973 Aug;48(4):620-8. View Related Products by Target Histamine Receptor

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₁H₁₈N₄O₄S

[ Molecular Weight ]:
302.350

[ Exact Mass ]:
302.104889

Related Compounds

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