R-Avanafil

Names

[ Name ]:
R-Avanafil

Biological Activity

[Description]:

(R)-Avanafil ((R)-TA1790) is a selective PDE5 inhibitor (IC50: 5.2 nM). (R)-Avanafil can be used for research of erectile dysfunction[1].

[Related Catalog]:

Research Areas >> Endocrinology

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)

[Target]

5.2 nM (PDE5)[1].

[References]

[1]. Sakamoto T, et al. The discovery of avanafil for the treatment of erectile dysfunction: a novel pyrimidine-5-carboxamide derivative as a potent and highly selective phosphodiesterase 5 inhibitor. Bioorg Med Chem Lett. 2014 Dec 1;24(23):5460-5.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₆ClN₇O₃

Related Compounds

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