1,4-Butane sultone
Names
[ CAS No. ]:
1633-83-6
[ Name ]:
1,4-Butane sultone
[Synonym ]:
1,2-Oxathiane, 2,2-dioxide
oxathiane 2,2-dioxide
1,4-Butane sultone
EINECS 216-647-9
MFCD00006584
1,2-Oxathiane 2,2-dioxide
1,4-Butanesultone
1.4-Butane Sultone
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
299.9±9.0 °C at 760 mmHg
[ Melting Point ]:
12.5-15ºC
[ Molecular Formula ]:
C4H8O3S
[ Molecular Weight ]:
136.169
[ Flash Point ]:
135.2±18.7 °C
[ Exact Mass ]:
136.019409
[ PSA ]:
51.75000
[ LogP ]:
-0.13
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.471
[ Water Solubility ]:
54 g/L (20 ºC) decomposes
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RP4300000
- CHEMICAL NAME :
- 1,2-Oxathiane, 2,2-dioxide
- CAS REGISTRY NUMBER :
- 1633-83-6
- BEILSTEIN REFERENCE NO. :
- 0110588
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 20
- MOLECULAR FORMULA :
- C4-H8-O3-S
- MOLECULAR WEIGHT :
- 136.18
- WISWESSER LINE NOTATION :
- T6OSWTJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 350 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 270 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 138 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1300 mg/kg/1Y-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Brain and Coverings - tumors Reproductive - Tumorigenic effects - ovarian tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2280 mg/kg/76W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1680 mg/kg/42W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
MUTATION DATA
- TYPE OF TEST :
- Morphological transformation
- TEST SYSTEM :
- Rodent - hamster Embryo
- DOSE/DURATION :
- 5 mg/L
- REFERENCE :
- IJCNAW International Journal of Cancer. (International Union Against Cancer, 3 rue du Conseil- General, 1205 Geneva, Switzerland) V.1- 1966- Volume(issue)/page/year: 19,642,1977
Safety Information
[ Symbol ]:
GHS07, GHS08
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H351
[ Precautionary Statements ]:
P301 + P312 + P330
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R22;R68
[ Safety Phrases ]:
S36/37-S45
[ RIDADR ]:
UN 2810
[ WGK Germany ]:
3
[ RTECS ]:
RP4300000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)
[ HS Code ]:
29349990
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934991000
[ Summary ]:
2934991000. sultones and sultams. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Carbohydr. Polym. 93(1) , 184-90, (2013)
For the development of renewable bioproducts able to solubilize organic persistent pollutant such as benzo[a]pyrene (BaP), modified potato starch was synthesized by alkylation. The addition of alkyl c...
Determination of the substituent distribution in O-sulfonylbutyl-(1-->4)-glucans.Carbohydr. Res. 327(3) , 275-85, (2000)
A method has been developed to determine the distribution of substituents in the glucose units of sulfonylbutylethers of cyclomaltoheptaose (beta-cyclodextrin). This method involves hydrolysis of the ...
Formation of unexpected substitution patterns in sulfonylbutylation of cyclomaltoheptaose promoted by host-guest interaction.Carbohydr. Res. 327(3) , 269-74, (2000)
The distribution of substituents in sulfonylbutylethers of cyclomaltoheptaose (beta-cyclodextrin) formed in aqueous medium has been determined by gas chromatography after hydrolysis and formation of t...