Orbofiban acetate

Names

[ Name ]:
Orbofiban acetate

[Synonym ]:
ethyl 3-[[(3S)-1-(4-carbamimidoylphenyl)-2-oxo-pyrrolidin-3-yl]carbamoylamino]propanoate
CS-511
Orbofiban acetate

Biological Activity

[Description]:

Orbofiban acetate is an orally active platelet GPIIb/IIIa antagonist that inhibits platelet aggregation.

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Cytoskeleton >> Integrin

[References]

[1]. Nicholson NS, Abood NA, Panzer-Knodle SG, et al. Orbofiban: an orally active GPIIb/IIIa platelet receptor antagonist. Med Res Rev. 2001;21(3):211-226.

Chemical & Physical Properties

[ Boiling Point ]:
776.9ºC at 760 mmHg

[ Molecular Formula ]:
C₁₉H₂₇N₅O₆

[ Molecular Weight ]:
421.45

[ Flash Point ]:
423.7ºC

[ Exact Mass ]:
421.19600

[ PSA ]:
178.40000

[ LogP ]:
1.87960

[ Vapour Pressure ]:
2.09E-25mmHg at 25°C

Related Compounds

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