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Ranevetmab

Names

[ CAS No. ]:
1632282-27-9

[ Name ]:
Ranevetmab

Biological Activity

[Description]:

Ranevetmab (NV-01) is a caninised anti-NGF monoclonal antibody (mAb). Ranevetmab can alleviate pain, and is used for the research of degenerative joint disease (DJD) pain[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[Target]

NGF


[In Vivo]

Ranevetmab (200 μg/kg,静脉注射) 减轻狗的退行性关节病 (DJD) 疼痛[1]。 Animal Model: Dogs with degenerative joint disease (DJD) pain[2] Dosage: 200 μg/kg Administration: i.v. Result: Improved canine brief pain inventory (CBPI), pain severity (PS) and pain interference (PI) scores.

[References]

[1]. Lascelles BD, et al. A canine-specific anti-nerve growth factor antibody alleviates pain and improves mobility and function in dogs with degenerative joint disease-associated pain. BMC Vet Res. 2015 Apr 30;11:101.  

Chemical & Physical Properties

No Any Chemical & Physical Properties


Related Compounds

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