Cimicifugoside H1

Names

[ Name ]:
Cimicifugoside H1

[Synonym ]:
Cimifugoside H 1
CiMicifugoside H

Biological Activity

[Description]:

Cimicifugoside H-1, a cyclolanostanol xyloside, is a major constituent of C. foetida L. extract. Cimicifugoside H-1 inhibits bone resorption and ovariectomy-induced bone loss[1][2][3].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Koeda M, et, al. Studies on the Chinese crude drug "shoma." IX. Three novel cyclolanostanol xylosides, cimicifugosides H-1, H-2 and H-5, from cimicifuga rhizome. Chem Pharm Bull (Tokyo). 1995 May;43(5):771-6.

[2]. Gai YY, et, al. Pharmacokinetics and bioavailability of cimicifugosides after oral administration of Cimicifuga foetida L. extract to rats. J Ethnopharmacol. 2012 Aug 30;143(1):249-55.

[3]. Li JX, et, al. Triterpenoids from Cimicifugae rhizoma, a novel class of inhibitors on bone resorption and ovariectomy-induced bone loss. Maturitas. 2007 Sep 20;58(1):59-69.

Chemical & Physical Properties

[ Density]:
1.31±0.1 g/cm3 at 760 mmHg

[ Boiling Point ]:
748.9±60.0 °C at 760 mmHg

[ Melting Point ]:
260-262 °C

[ Molecular Formula ]:
C₃₇H₅₄O₁₁

[ Molecular Weight ]:
674.81800

[ Exact Mass ]:
674.36700

[ PSA ]:
172.35000

[ LogP ]:
2.63390

[ Storage condition ]:
2-8°C

Cimicifugoside H1

Names

Biological Activity

Chemical & Physical Properties

Related Compounds