Eg5-IN-2

Names

[ CAS No. ]:
1629735-05-2

[ Name ]:
Eg5-IN-2

Biological Activity

[Description]:

Eg5-IN-2 (Compound Scaffold B (4)) is an Eg5 inhibitor (IC50: < 0.5 nM). Eg5-IN-2 can be used as an ADC payload for synthesis of ADCs[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Cytotoxin

[References]

[1]. Karpov AS, et al. Discovery of Potent and Selective Antibody-Drug Conjugates with Eg5 Inhibitors through Linker and Payload Optimization. ACS Med Chem Lett. 2019 Dec 3;10(12):1674-1679.  

Chemical & Physical Properties

[ Molecular Formula ]:
C31H38F3N5O3

[ Molecular Weight ]:
585.66

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.