Olinciguat

Names

[ Name ]:
Olinciguat

Biological Activity

[Description]:

Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator with concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole cell assay[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> GPCR/G Protein >> Guanylate Cyclase

[References]

[1]. Buys ES, et al. Discovery and development of next generation sGC stimulators with diverse multidimensional pharmacology and broad therapeutic potential. Nitric Oxide. 2018 Aug 1;78:72-80.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₁₆F₅N₇O₃

[ Molecular Weight ]:
509.39