LY3202626

Names

[ Name ]:
LY3202626

[Synonym ]:
2-Pyrazinecarboxamide, N-[3-[(4aR,7aS)-2-amino-6-(5-fluoro-2-pyrimidinyl)-4a,5,6,7-tetrahydropyrrolo[3,4-d][1,3]thiazin-7a(4H)-yl]-4-fluorophenyl]-5-methoxy-
N-{3-[(4aR,7aS)-2-Amino-6-(5-fluoro-2-pyrimidinyl)-4a,5,6,7-tetrahydropyrrolo[3,4-d][1,3]thiazin-7a(4H)-yl]-4-fluorophenyl}-5-methoxy-2-pyrazinecarboxamide

Biological Activity

[Description]:

LY3202626 is a small molecule non-selective BACE1 inhibitor, causes dose-dependent reductions in CSF and plasma Aβ concentrations, shows potential for the treatment of Alzheimer's disease. Alzheimer Disease Phase 2 Clinical

[References]

References View Related Products by Target Beta-secretase (BACE) Alzheimer Disease

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Molecular Formula ]:
C₂₂H₂₀F₂N₈O₂S

[ Molecular Weight ]:
498.508

[ Exact Mass ]:
498.139801

[ LogP ]:
3.08

[ Index of Refraction ]:
1.750

Related Compounds

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