DCC-3014

Names

[ Name ]:
DCC-3014

Biological Activity

[Description]:

DCC-3014 is a c-FMS (CSF-IR) and c-Kit dual inhibitor extracted from patent WO2014145025A2, Compound Example 10, has IC50s of <0.01 μM and 0.1-1 μM, respectively[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> c-Fms

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> c-Kit

[Target]

IC50: <0.01 μM (c-FMS/CSF-IR), 0.1-1 μM (c-Kit)[1]

[In Vitro]

DCC-3014 is a c-FMS (CSF-IR) and c-Kit dual inhibitor with anti-cancer and anti-proliferative activities[1].

[References]

[1]. Yumi Ahn, et al. 2-aminopyrimidin-6-ones and analogs exhibiting anti-cancer and anti-proliferative activities. WO2014145025A2.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₅N₇O₂

[ Molecular Weight ]:
431.49

DCC-3014

Names

Biological Activity

Chemical & Physical Properties

Related Compounds