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Caspofungin

Names

[ CAS No. ]:
162808-62-0

[ Name ]:
Caspofungin

[Synonym ]:
Caspofungin
m991
PORFUNGIN
POFUNGIN

Biological Activity

[Description]:

Caspofungin is a potent antifungal agent. Caspofungin inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan[1][2].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Fungal

[References]

[1]. Flattery AM, et, al. Efficacy of caspofungin in a juvenile mouse model of central nervous system candidiasis. Antimicrob Agents Chemother. 2011 Jul;55(7):3491-7.

[2]. Mojumder DK, et, al. Evaluating retinal toxicity of intravitreal caspofungin in the mouse eye. Invest Ophthalmol Vis Sci. 2010 Nov;51(11):5796-803.

Chemical & Physical Properties

[ Density]:
1.36g/cm3

[ Boiling Point ]:
1408.1ºC at 760mmHg

[ Molecular Formula ]:
C53H89N9O15

[ Molecular Weight ]:
1092.33000

[ Flash Point ]:
805.4ºC

[ Exact Mass ]:
1091.65000

[ PSA ]:
400.00000

[ LogP ]:
0.76120

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.623

[ Storage condition ]:
2-8°C

Related Compounds