DB21, Galectin-1 Antagonist

Names

[ CAS No. ]:
1623027-80-4

[ Name ]:
DB21, Galectin-1 Antagonist

Biological Activity

[Description]:

DB21, Galectin-1 Antagonist is a dibenzofuran conjugated peptidomimetic that acts as an allosteric inhibitor of galectin-1 (GAL1)binding to cell surface glycans. DB21, Galectin-1 Antagonis increases inhibition of angiogenesis and tumour growth in melanoma, lung adenocarcinoma and ovarian cancer models[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Karina V Mariño, et al. Targeting galectin-driven regulatory circuits in cancer and fibrosis. Nat Rev Drug Discov. 2023 Apr;22(4):295-316.  

Chemical & Physical Properties

[ Molecular Formula ]:
C83H136N18O19

[ Molecular Weight ]:
1690.08

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.